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Two Blind Mice and a Wild-Type

CITE THIS QUILT

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Cite this Quilt

Conley, Shanno. Two Blind Mice and a Wild-Type. 2015. From Michigan State University Museum, Michigan Quilt Project; Michigan State University Museum; Quilts and Health. Published in The Quilt Index, https://quiltindex.org/view/?type=fullrec&kid=12-8-10523. Accessed: 03/02/21

QUILT INDEX RECORD

12-8-10523

Essay about this quilt.

These diseases lack effective cures/treatments, due largely to an ongoing lack of knowledge about the underlying disease mechanisms. Knockout and knockin mice are genetically engineered to carry mutations in their genome to model debilitating diseases, critical since it is difficult to study many diseases in human patients. The scientific and medical advancements that have resulted from use of these models cannot be overstated, and much of our knowledge about these diseases is a direct result of the use of these animal models. This quilt re-interprets my fluorescein angiograms--pictures of the blood vessels in the eye--from mice with diabetic retinopathy (top) and macular dystrophy (bottom), as well as their normal or wild-type counterpart (middle). We use these specialized mice to study the pathobiological mechanisms associated with these blinding retinal degenerations and to develop and test novel treatments. I created this piece to help bring to light the crucial role that biomedical research and model systems play in fostering our understanding of critical human diseases.

Who documented this quilt?

Michigan Quilt Project; Michigan State University Museum; Quilts and Health

Where are the records for this quilt housed?

Michigan State University Museum, Quilts and Health

Michigan Quilt Project Number

QHB-3.25

If this quilt is owned by a museum, enter the accession number here

2018:2.1

What is the title of the quilt?

Two Blind Mice and a Wild-Type

What is the subject of the quilt?

Eye disease

When was the form filled out?

2016

Who made the quilt top?

Conley, Shannon

Who did the quilting?

Conley, Shannon

Where was the quilt made (city)?

Moore

Where was the quilt made (state)?

Oklahoma (OK)

Where was the quilt made (country)?

United States

Choose the time frame that best describes when the quilt was made.

2000-2025

When was the quilt finished?

2015

This quilt was made to be used as a

Art or personal expression

How is this quilt used?

Museum collection

What type of quilted object is this?

Finished quilt

How wide is the quilt?

20"

How long is the quilt?

30"

What color(s) is the quilt?

Blue, Gold

What is the best description of the quilt's condition?

Excellent/like new

What types of fiber were used to make the quilt top?

Cotton

What piecing method was used to make the quilt top?

Machine Piecing

What embellishments were used to make the quilt top?

Painting

What embellishment materials were used to make the quilt top?

Beads attached

How are the quilt layers held together?

Machine quilting

Ownership of this quilt is:

Public- Michigan State University Museum

Quilt owner's city:

East Lansing

Quilt owner's county:

Ingham

Quilt owner's state.

Michigan (MI)

Quilt owner's country:

United States

How did the owner acquire this quilt?

Purchase

Access and copyright information:

Restricted

Who photographed this quilt?

Pearl Yee Wong