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Two Blind Mice and a Wild-Type

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quilt

QUILT INDEX RECORD

12-8-10523

Who documented this quilt?

Michigan Quilt Project; Michigan State University Museum Collection; Quilts and Health

Where are the records for this quilt housed?

Michigan State University Museum

Michigan Quilt Project Number:

QHB-3.25

If this quilt is owned by a museum, enter the accession number:

2018:2.1

Essay:

These diseases lack effective cures/treatments, due largely to an ongoing lack of knowledge about the underlying disease mechanisms. Knockout and knockin mice are genetically engineered to carry mutations in their genome to model debilitating diseases, critical since it is difficult to study many diseases in human patients. The scientific and medical advancements that have resulted from use of these models cannot be overstated, and much of our knowledge about these diseases is a direct result of the use of these animal models. This quilt re-interprets my fluorescein angiograms--pictures of the blood vessels in the eye--from mice with diabetic retinopathy (top) and macular dystrophy (bottom), as well as their normal or wild-type counterpart (middle). We use these specialized mice to study the pathobiological mechanisms associated with these blinding retinal degenerations and to develop and test novel treatments. I created this piece to help bring to light the crucial role that biomedical research and model systems play in fostering our understanding of critical human diseases.

Quilt's title:

Two Blind Mice and a Wild-Type

Subject of the quilt:

Eye disease

When was the form filled out?

2016

Quilt top made by:

Conley, Shannon

Quilted by:

Conley, Shannon

Where the quilt was made, city:

Moore

Where the quilt was made, state:

Oklahoma (OK)

Where the quilt was made, country:

United States

Time period:

2000-2025

When was the quilt finished?

2015

Why was the quilt made?

Art or personal expression

Quilt is presently used as:

Museum collection

This is a:

Finished quilt

How wide is the quilt?

20"

How long is the quilt?

30"

What color is the quilt?

Blue; Gold

Quilt's condition:

Excellent/like new

Fiber types used to make the quilt top:

Cotton

Piecing techniques used to make the quilt top:

Machine Piecing

Embellishment techniques used to make the quilt top:

Painting

Embellishments used:

Beads attached

How are the layers held together?

Machine quilting

Ownership of this quilt is:

Public- Michigan State University Museum

Quilt owner's city:

East Lansing

Quilt owner's county:

Ingham

Quilt owner's state:

Michigan (MI)

Quilt owner's country:

United States

How was this quilt acquired?

Purchase

Access and copyright information:

Restricted

Who photographed this quilt?

Pearl Yee Wong

Cite this Quilt

Conley, Shanno. Two Blind Mice and a Wild-Type. 2015. From Michigan State University Museum, Michigan Quilt Project; Michigan State University Museum Collection; Quilts and Health. Published in The Quilt Index, https://quiltindex.org/view/?type=fullrec&kid=12-8-10523. Accessed: 04/23/24